Why off-label drug prescribing is off its head

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drug bottles and pills

Off-label drug prescribing is now all the rage.

A recent report stated that Seroquel (Quetiapine) is now being used for sedation, depression and anxiety disorders.

It was originally used as a psychotic agent, along with Zyprexa and Risperdal, and was used mainly for poor old ladies (but not men) locked up in nursing homes — just before the makers of Soylent Green took over.

Old lady jaw melt

Many old ladies were also pumped full of bi-phosphonates to treat their osteoporosis when really they should have spent more time in the sun and never used sunscreen.

But an unfortunate side-effect of all this old lady bi-phosphonate-pumping was jaw necrosis, where the jaw just melted away.

Still, it stopped them from complaining.

Seroquel, Zyprexa and Risperdal are now used for treating children with ADHD and autism (also off-label).

To have children being assaulted by Ritalin and amphetamines is already bad enough, but adding the anti-psychotics is a direct attack on  their still-evolving brain chemistry.

Somehow or other, doctors and psychiatrists have been convinced by Astra-Zeneca — a European/American conglomerate — to treat all these conditions they were never given approval for. Perhaps paid trips to very important conferences in Basle, Geneva and Disneyland may have something to do with it.

A crumbling insomniac

As well as crumbling in all directions, I have always had trouble sleeping.

I saw the local doctor and described the “restless legs” syndrome where I wrung my hands, twitched legs, rubbed my scalp and refused to nod off until 3 or 4am.

He mentioned that an off-label supply of Levodopa would be worth a try.

This was used for Parkinson’s disease and seriously messed with your brain chemistry, and I thought my brain chemistry was pretty messy anyway. I tried it for three nights and then gave up — it didn’t work and no-one could ever assess what harm it was doing.

Nudity cures my insomnia

I solved the problem of sleepless nights by going out into the garden with little or no clothes on (this is the horrifying part of the story), staying there until I started freezing and shivering and then went back to bed and slept.

This was cheaper and my brain chemistry stayed intact, though perhaps some minor changes would have helped. For example, brain chemistry alterations to help me believe that TV reality shows are real and to understand why we have a plethora of TV cooking shows in a nation that doesn’t cook.

Related Post:
Why I’m the world’s most inept drug pusher

Robert Gosstray

Robert Gosstray is a retired pharmacist and the resident health writer for Midlifexpress. He is the author of The Pharmacist's Secrets: Drugs, lies and money.

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